Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos |
| Phenotype | phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | BIOCARTA_KERATINOCYTE DIFFERENTIATION |
| Enrichment Score (ES) | -0.6853303 |
| Normalized Enrichment Score (NES) | -1.8563578 |
| Nominal p-value | 0.001953125 |
| FDR q-value | 0.02008166 |
| FWER p-Value | 0.067 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HRAS | 1422407_s_at 1424132_at | 1741 | 0.725 | -0.0592 | No | ||
| 2 | MAPK14 | 1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at | 2079 | 0.612 | -0.0575 | No | ||
| 3 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 2363 | 0.538 | -0.0554 | No | ||
| 4 | RIPK1 | 1419508_at 1439273_at 1449485_at | 2524 | 0.504 | -0.0486 | No | ||
| 5 | PPP2R5D | 1450560_a_at | 2644 | 0.481 | -0.0405 | No | ||
| 6 | SHC1 | 1422853_at 1422854_at | 2961 | 0.426 | -0.0430 | No | ||
| 7 | TRAF1 | 1423602_at 1445452_at | 3159 | 0.394 | -0.0410 | No | ||
| 8 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 3406 | 0.363 | -0.0421 | No | ||
| 9 | MAP2K6 | 1426850_a_at 1459292_at | 4140 | 0.298 | -0.0672 | No | ||
| 10 | PRKCE | 1437860_at 1437861_s_at 1442609_at 1444649_at 1449956_at 1452878_at | 4192 | 0.295 | -0.0613 | No | ||
| 11 | MAP4K4 | 1422615_at 1440609_at 1448050_s_at 1459912_at | 4839 | 0.259 | -0.0835 | No | ||
| 12 | PLAT | 1415806_at 1458553_at | 6141 | 0.207 | -0.1372 | No | ||
| 13 | MAP2K3 | 1425456_a_at 1451714_a_at | 7235 | 0.171 | -0.1823 | No | ||
| 14 | SP1 | 1418180_at 1448994_at 1454852_at | 8439 | 0.138 | -0.2334 | No | ||
| 15 | EGF | 1418093_a_at | 8460 | 0.138 | -0.2305 | No | ||
| 16 | MAPK13 | 1448871_at | 8634 | 0.134 | -0.2346 | No | ||
| 17 | TNF | 1419607_at | 9455 | 0.113 | -0.2689 | No | ||
| 18 | EGFR | 1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at | 13159 | 0.025 | -0.4374 | No | ||
| 19 | CEBPA | 1418982_at | 13373 | 0.019 | -0.4466 | No | ||
| 20 | JUN | 1417409_at 1448694_at | 14497 | -0.014 | -0.4976 | No | ||
| 21 | MAPK3 | 1427060_at | 14783 | -0.022 | -0.5100 | No | ||
| 22 | HOXA7 | 1449499_at | 15025 | -0.030 | -0.5201 | No | ||
| 23 | RAF1 | 1416078_s_at 1425419_a_at | 15837 | -0.063 | -0.5554 | No | ||
| 24 | FASLG | 1418803_a_at 1449235_at | 15860 | -0.064 | -0.5546 | No | ||
| 25 | IKBKG | 1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at | 15968 | -0.069 | -0.5576 | No | ||
| 26 | MAP2K1 | 1416351_at | 16232 | -0.082 | -0.5673 | No | ||
| 27 | PRKCA | 1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at | 16402 | -0.092 | -0.5725 | No | ||
| 28 | PRKCD | 1422847_a_at 1442256_at | 17365 | -0.167 | -0.6118 | No | ||
| 29 | DAXX | 1419026_at | 17440 | -0.174 | -0.6102 | No | ||
| 30 | PRKCH | 1422079_at 1434248_at | 17855 | -0.218 | -0.6230 | No | ||
| 31 | TRAF2 | 1451233_at | 18355 | -0.288 | -0.6378 | No | ||
| 32 | GRB2 | 1418508_a_at 1449111_a_at | 18989 | -0.393 | -0.6557 | No | ||
| 33 | SOS1 | 1421884_at 1421885_at 1421886_at | 19240 | -0.448 | -0.6546 | No | ||
| 34 | MAP2K4 | 1426233_at 1442679_at 1451982_at | 19388 | -0.482 | -0.6478 | No | ||
| 35 | RELA | 1419536_a_at | 19403 | -0.485 | -0.6348 | No | ||
| 36 | TNFRSF1A | 1417291_at | 20509 | -0.875 | -0.6608 | Yes | ||
| 37 | CHUK | 1417091_at 1428210_s_at 1451383_a_at | 20646 | -0.945 | -0.6406 | Yes | ||
| 38 | FOS | 1423100_at | 20795 | -1.059 | -0.6177 | Yes | ||
| 39 | BIRC2 | 1418854_at | 20801 | -1.062 | -0.5882 | Yes | ||
| 40 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 20911 | -1.157 | -0.5608 | Yes | ||
| 41 | FAS | 1460251_at | 20997 | -1.242 | -0.5299 | Yes | ||
| 42 | MAP3K1 | 1424850_at | 21036 | -1.286 | -0.4956 | Yes | ||
| 43 | PRKCQ | 1426044_a_at | 21352 | -1.700 | -0.4624 | Yes | ||
| 44 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 21434 | -1.870 | -0.4137 | Yes | ||
| 45 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 21462 | -1.936 | -0.3607 | Yes | ||
| 46 | NFKBIA | 1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at | 21592 | -2.242 | -0.3038 | Yes | ||
| 47 | ETS1 | 1422027_a_at 1422028_a_at 1426725_s_at 1452163_at | 21652 | -2.465 | -0.2375 | Yes | ||
| 48 | IKBKB | 1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at | 21683 | -2.583 | -0.1665 | Yes | ||
| 49 | ETS2 | 1416268_at 1437809_x_at 1447685_x_at | 21704 | -2.710 | -0.0915 | Yes | ||
| 50 | BIRC3 | 1421392_a_at 1425223_at | 21874 | -3.643 | 0.0028 | Yes |
